pip install require tls/ssl

pip install require tls/ssl - python

I have got a problem with install python on my OVH vps server kubuntu 14.04 desktop. What i need to do ?
:~/Desktop# python get-pip.py
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
Collecting pip
Could not fetch URL https://pypi.python.org/simple/pip/: There was a problem confirming the ssl certificate: Can't connect to HTTPS URL because the SSL module is not available. - skipping
Could not find a version that satisfies the requirement pip (from versions: )
No matching distribution found for pip

Calling more attention to #Arduino_Sentinel 's comment
Sounds like you installed Python by running make, right ? In that case I'd recommend installing libssl-dev and rebuilding+reinstalling Python
On a fresh debian installation, I had installed Python 3.6 via
wget https://www.python.org/ftp/python/3.6.3/Python-3.6.3.tgz
tar xvf Python-3.6.3.tgz
cd Python-3.6.3
./configure
make
make altinstall
creating a virtualenv with virtualenv -p python3.6 env and subsequently trying to install anything with env/bin/pip would produce the errors from the question.
The comment quoted above solved the issue on my server.
The main problem is you compiling python before install the libssl.

You should trying installing form your packages repos
sudo apt-get install python-pip

Related

Python get-pip.py fails due to site-package not writtable and SSL not available while they seem OK [duplicate]

I've install Python 3.4 and Python 3.6 on my local machine successfully, but am unable to install packages with pip3.
When I execute pip3 install <package>, I get the following SSL related error:
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
Collecting <package>
Could not fetch URL https://pypi.python.org/simple/<package>/: There was a problem confirming the ssl certificate: Can't connect to HTTPS URL because the SSL module is not available. - skipping
Could not find a version that satisfies the requirement <package> (from versions: )
No matching distribution found for <package>
How can I fix my Python3.x install so that I can install packages with pip install <package>?

Step by step guide to install Python 3.6 and pip3 in Ubuntu
Install the necessary packages for Python and ssl: $ sudo apt-get install libreadline-gplv2-dev libncursesw5-dev libssl-dev libsqlite3-dev tk-dev libgdbm-dev libc6-dev libbz2-dev
Download and unzip "Python-3.6.8.tar.xz" from https://www.python.org/ftp/python/ into your home directory.
Open terminal in that directory and run: $ ./configure
Build and install: $ make && sudo make install
Install packages with: $ pip3 install package_name
Disclaimer: The above commands are not tested in Ubuntu 20.04 LTS.

If you are on Windows and use anaconda this worked for me:
I tried a lot of other solutions which did not work (Environment PATH Variable changes ...)
The problem can be caused by DLLs in the Windows\System32 folder (e.g. libcrypto-1_1-x64.dll or libssl-1_1-x64.dll or others) placed there by other software.
The fix was installing openSSL from https://slproweb.com/products/Win32OpenSSL.html which replaces the dlls by more recent versions.

If you are on Red Hat/CentOS:
# To allow for building python ssl libs
yum install openssl-devel
# Download the source of *any* python version
cd /usr/src
wget https://www.python.org/ftp/python/3.6.2/Python-3.6.2.tar.xz
tar xf Python-3.6.2.tar.xz
cd Python-3.6.2
# Configure the build w/ your installed libraries
./configure
# Install into /usr/local/bin/python3.6, don't overwrite global python bin
make altinstall

I had a similar problem on OSX 10.11 due to installing memcached which installed python 3.7 on top of 3.6.
WARNING: pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
Spent hours on unlinking openssl, reinstalling, changing paths.. and nothing helped. Changing openssl version back from to older version did the trick:
brew switch openssl 1.0.2e
I did not see this suggestion anywhere in internet. Hope it serves someone.

In Ubuntu, this can help:
cd Python-3.6.2
./configure --with-ssl
make
sudo make install

Agree with the answer by mastaBlasta. Worked for me. I encountered the same problem as the topic description.
Environment: MacOS Sierra. And I use Homebrew.
My solution:
Reinstall openssl by brew uninstall openssl; brew install openssl
According to the hints given by Homebrew, do the following:
echo 'export PATH="/usr/local/opt/openssl/bin:$PATH"' >> ~/.bash_profile
export LDFLAGS="-L/usr/local/opt/openssl/lib"
export CPPFLAGS="-I/usr/local/opt/openssl/include"

I had the same issue with python3.8.5 installation on Debian9. I have done a build, but when I have tried to download some modules, pip3.8 issued following error:
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
I have searched for the root of my problem and found out that there is a system dependent portion of the python build which is called by system independent one. In case of missing ssl you just needed to open python terminal and check whether is _ssl present:
>>> help('modules')
.
.
_sre enum pwd wave
_ssl errno py_compile weakref
_stat faulthandler pyclbr webbrowser
.
.
If not your system dependent ssl module part is missing. You can check it also by listing content of <python_installation_root>/lib/python3.8/lib-dynload:
>ls ./lib/python3.8/lib-dynload | grep ssl
_ssl.cpython-38-x86_64-linux-gnu.so
The problem was caused as written by PengShaw by missing libssl-dev during the build. Therefore you have to follow the recommended python installation flow. First install prerequisites and then build and install the python. Installation without devel versions of libs resulted in my case in the missing system dependent part. In this case _ssl.
Note that the devel lib name differs for Debian and CentOS, therefore check whether the installation hints posted on net are suitable for your specific Linux system type:
For Debian:
sudo apt install -y libbz2-dev libffi-dev libssl-dev
./configure --enable-optimizations
make
make altinstall
For CentOS:
sudo yum -y install bzip2-devel libffi-devel openssl-devel
./configure --enable-optimizations
make
make altinstall
It is for sure a good idea to list configuration options prior the configuration and evtl. use some additional options:
./configure --help
Last but not least in case you use --prefix for a non-default installation location, remember to add your <python_installation_root>/lib to your LD_LIBRARY_PATH .

If you are on Windows and use Anaconda you can try running "pip install ..." command in Anaconda Prompt instead of cmd.exe, as user willliu1995 suggests here. This was the fastest solution for me, that does not require installation of additional components.

The problem probably caused by library missing.
Before you install python 3.6, make sure you install all the libraries required for python.
$ sudo apt-get install build-essential checkinstall
$ sudo apt-get install libreadline-gplv2-dev libncursesw5-dev libssl-dev libsqlite3-dev tk-dev libgdbm-dev libc6-dev libbz2-dev
More information in How to Install Python 3.6.0 on Ubuntu & LinuxMint

If you are on OSX and have compiled python from source:
Install openssl using brew brew install openssl
Make sure to follow the instructions brew gives you about setting your CPPFLAGS and LDFLAGS. In my case I am using the openssl#1.1 brew formula and I need these 3 settings for the python build process to correctly link to my SSL library:
export LDFLAGS="-L/usr/local/opt/openssl#1.1/lib"
export CPPFLAGS="-I/usr/local/opt/openssl#1.1/include"
export PKG_CONFIG_PATH="/usr/local/opt/openssl#1.1/lib/pkgconfig"
Assuming the library is installed at that location.

Downgrading openssl worked for me,
brew switch openssl 1.0.2s

I encountered the same problem on windows 10. My very specific issue is due to my installation of Anaconda. I installed Anaconda and under the path Path/to/Anaconda3/, there comes the python.exe. Thus, I didn't install python at all because Anaconda includes python. When using pip to install packages, I found the same error report, pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available..
The solution was the following:
1) you can download python again on the official website;
2) Navigate to the directory where "Python 3.7 (64-bit).lnk"is located
3) import ssl and exit()
4) type in cmd, "Python 3.7 (64-bit).lnk" -m pip install tensorflow for instance.
Here, you're all set.

I tried A LOT of ways to solve this problem and none solved. I'm currently on Windows 10.
The only thing that worked was:
Uninstall Anaconda
Uninstall Python (i was using version 3.7.3)
Install Python again (remember to check the option to automatically add to PATH)
Then I've downloaded all the libs I needed using PIP... and worked!
Don't know why, or if the problem was somehow related to Anaconda.

for osx brew users
my issue appeared related to my python installation and was quickly resolved by re-installing python3 and pip. i think it started misbehaving after an OS update but who knows (at this time I am on Mac OS 10.14.6)
brew reinstall python3 --force
# setup pip
curl https://bootstrap.pypa.io/get-pip.py -o get-pip.py
python3 get-pip.py
# installa pkg successfully
pip install pandas

You can do either of these two:
While installing Anaconda, select the option to add Anaconda to the path.
or
Find these (complete) paths from your installation folder of Anaconda and add them to the environment variable :
\Anaconda
\Anaconda\Library\mingw-w64\bin
\Anaconda\Library\usr\bin
\Anaconda\Library\bin
\Anaconda\Scripts
\anaconda\Library
\anaconda\condabin
Add the above paths to the "Path" system variable and it should show the error no more :)

The ssl module is a TLS/SSL wrapper for accessing Operation Sytem (OS) socket (Lib/ssl.py). So when ssl module is not available, chances are that you either don't have OS OpenSSL libraries installed, or those libraries were not found when you install Python. Let assume it is a later case (aka: you already have OpenSSL installed, but they are not correctly linked when installing Python).
I will also assume you are installing from source. If you are installing from binary (ie: Window .exe file), or package (Mac .dmg, or Ubuntu apt), there is not much you can do with the installing process.
During the step of configuring your python installation, you need to specify where the OS OpenSSL will be used for linking:
# python 3.8 beta
./configure --with-openssl="your_OpenSSL root"
So where will you find your installed OpenSSL directory?
# ubuntu
locate ssl.h | grep '/openssl/ssl.h'
/home/user/.linuxbrew/Cellar/openssl/1.0.2r/include/openssl/ssl.h
/home/user/envs/py37/include/openssl/ssl.h
/home/user/miniconda3/envs/py38b3/include/openssl/ssl.h
/home/user/miniconda3/include/openssl/ssl.h
/home/user/miniconda3/pkgs/openssl-1.0.2s-h7b6447c_0/include/openssl/ssl.h
/home/user/miniconda3/pkgs/openssl-1.1.1b-h7b6447c_1/include/openssl/ssl.h
/home/user/miniconda3/pkgs/openssl-1.1.1c-h7b6447c_1/include/openssl/ssl.h
/usr/include/openssl/ssl.h
Your system may be different than mine, but as you see here I have many different installed openssl libraries. As the time of this writing, python 3.8 expects openssl 1.0.2 or 1.1:
Python requires an OpenSSL 1.0.2 or 1.1 compatible libssl with X509_VERIFY_PARAM_set1_host().
So you would need to verify which of those installed libraries that you can use for linking, for example
/usr/bin/openssl version
OpenSSL 1.0.2g 1 Mar 2016
./configure --with-openssl="/usr"
make && make install
You may need to try a few, or install a new, to find the library that would work for your Python and your OS.

I was having the same issue and was able to resolve with the following steps:
sudo yum install -y libffi-devel
sudo yum install openssl-devel
cd /usr/src
sudo wget https://www.python.org/ftp/python/3.7.1/Python-3.7.1.tar.xz
sudo tar xf Python-3.7.1.tar.xz
cd Python-3.7.1
sudo ./configure --enable-optimizations
# Install into /usr/local/bin/python3.7, don't overwrite global python bin
sudo make altinstall
depending on perms, you may not need sudo.
Results:
Collecting setuptools
Collecting pip
Installing collected packages: setuptools, pip
Successfully installed pip-10.0.1 setuptools-39.0.1
should now be able to run
python3.7 -V
and
pip3.7 -V
When installing packages:
pip3.7 install pandas
or depending on perms, you can also add the --user flag like so:
pip3.7 install pandas --user

In my case with using Mac, I deleted
/Applications/Python 3.7.
because I already had Python3.7 by brew install python3 .
But it was a trigger of the message
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
What I did in my situation
I downloaded macOS 64-bit installer again, and installed.
Double click /Applications/Python3.6/Install Certificates.command and /Applications/Python3.6/Update Shell Profile.command.
Reboot mac
And I am not sure but possibly contributed to succeed is pip.conf. See pip install fails.

I finally solve this issue. These are the detail of my env:
Version of Python to install: 3.6.8
OS: Ubuntu 16.04.6 LTS
Root access: No
Some people suggest to install libssl-dev, but it did not work for me. I follow this link and I fixed it!
In short, I download, extract, build, and install OpenSSL (openssl-1.1.1b.tar.gz). Then, I modify .bashrc file follow this link.
Next, I download and extract Python-3.6.8.tgz. I edit Modules/Setup.dist to modify SSL path (lines around #211). I did ./configure --prefix=$HOME/opt/python-3.6.8, make and make install. Last, I modify my .bashrc. Notice that I do not include --enable-optimizations in ./configure.

I was able to fix this by updating the python version in this file.
pyenv: version `3.6.5' is not installed (set by /Users/taruntarun/.python-version)
Though i had the latest version installed, my command was still using old version 3.6.5
Moving to version 3.7.3

Termux
This worked because i didnt have an existing openssl version installed.
pkg install openssl-tool

If you are on OSX and in case the other solutions didn't work for you (just like me).
You can try uninstalling python3 and upgrade pip3
brew uninstall --ignore-dependencies python3
pip3 install --upgrade pip
This worked for me ;)

(NOT on Windows!)
This made me tear my hair out for a week, so I hope this will help someone
I tried everything short of re-installing Anaconda and/or Jupyter.
Setup
AWS Linux
Manually installed Anaconda 3-5.3.0
Python3 (3.7) was running inside anaconda (ie, ./anaconda3/bin/python)
there was also /usr/bin/python and /usr/bin/python3 (but these were not being used as most of the work was done in Jupyter's terminal)
Fix
In Jupyter's terminal:
cp /usr/lib64/libssl.so.10 ./anaconda3/lib/libssl.so.1.0.0
cp /usr/lib64/libcrypto.so.10 ./anaconda3/lib/libcrypto.so.1.0.0
What triggered this?
So, this was all working until I tried to do a conda install conda-forge
I'm not sure what happened, but conda must have updated openssl on the box (I'm guessing) so after this, everything broke.
Basically, unknown to me, conda had updated openssl, but somehow deleted the old libraries and replaced it with libssl.so.1.1 and libcrypto.so.1.1.
Python3, I guess, was compiled to look for libssl.so.1.0.0
In the end, the key to diagnosis was this:
python -c "import ssl; print (ssl.OPENSSL_VERSION)"
gave the clue library "libssl.so.1.0.0" not found
The huge assumption I made is that the yum version of ssl is the same as the conda version, so just renaming the shared object might work, and it did.
My other solution was to re-compile python, re-install anaconda, etc, but in the end I'm glad I didn't need to.
Hope this helps you guys out.

In the case of using pyenv to manage python installations on Mac OS Catalina, I had to install openssl with brew first and then after that run pyenv install 3.7.8 which seemed to build the python installation using the openssl from homebrew (it even said as such in the installation output). Then pyenv global 3.7.8 and I was away.

On macos, configure python 3.8.1 with the command below will solve the problem, i think it would also work on Linux.
./configure --enable-optimizations --with-openssl=/usr/local/opt/openssl#1.1/
change the dir parameter based on your system.

I've made some PATH changes to mimic part of the Anaconda Powershell Prompt $env:PATH
C:\Users\merheb\Miniconda3;C:\Users\merheb\Miniconda3\Library\mingw-w64\bin;C:\Users\merheb\Miniconda3\Library\usr\bin;C:\Users\merheb\Miniconda3\Library\bin;C:\Users\merheb\Miniconda3\Scripts;C:\Users\merheb\Miniconda3\bin;C:\Users\merheb\Miniconda3\condabin;
And It worked for me.

Building from source was what worked for me on Ubuntu 22.10:
Install OpenSSL manually, tested here with OpenSSL 1.1.1s, extracted then ran:
./config --prefix='/opt/openssl' --openssldir='/opt/ssl'
make
make install
Then with your older Python 3 version (here Python-3.8.16) run:
export LD_RUN_PATH='/opt/openssl/lib'
export CC='gcc-12' # sudo apt install gcc-12
./configure --enable-optimizations \
--with-openssl='/opt/openssl' \
--prefix='/opt/python/3.8' -C
make
make install
Test with:
/opt/python/3.8/bin/python3 -c 'import ssl; print(ssl.OPENSSL_VERSION)'
OpenSSL 1.1.1s 1 Nov 2022

The python documentation is actually very clear, and following the instructions did the job whereas other answers I found here were not fixing this issue.
first, install python 3.x.x from source using, for example with version 3.6.2 https://www.python.org/ftp/python/3.6.2/Python-3.6.2.tar.xz
make sure you have openssl installed by running brew install openssl
unzip it and move to the python directory: tar xvzf Python-3.6.2.tar.xz && cd Python-3.6.2
then if the python version is < 3.7, run
CPPFLAGS="-I$(brew --prefix openssl)/include" \
LDFLAGS="-L$(brew --prefix openssl)/lib" \
./configure --with-pydebug
5. finallly, run make -s -j2 (-s is the silent flag, -j2 tells your machine to use 2 jobs)

I had the same issue trying to install python3.7 on an ubuntu14.04 machine.
The issue was that I had some custom folders in my PKG_CONFIG_PATH and in my LD_LIBRARY_PATH, which prevented the python build process to find the system openssl libraries.
so try to clear them and see what happens:
export PKG_CONFIG_PATH=""
export LD_LIBRARY_PATH=""

Ok the latest answer to this, as of now don't use Python 3.8, use only 3.7 or less , because of most of the libraries fail to install with the above error

Why can't I install Rasa on OSX? "There was a problem confirming the ssl certificate"

I am trying to run the following command on my macbook inside a virtualenv...
pip3 install rasa
but when I run I get
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
Collecting rasa
Could not fetch URL https://pypi.python.org/simple/rasa/: There was a problem confirming the ssl certificate: Can't connect to HTTPS URL because the SSL module is not available. - skipping
Could not find a version that satisfies the requirement rasa (from versions: )
No matching distribution found for rasa
I tried install openSSL 3 like this but I am getting the same error.

Given that you're on Mac you're gonna have an easier time if you go through homebrew
If you do not have Homebrew:
/usr/bin/ruby -e "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/master/install)"
Or if you already have Homebrew installed:
brew update && brew upgrade
brew uninstall --ignore-dependencies openssl; brew install https://github.com/tebelorg/Tump/releases/download/v1.0.0/openssl.rb

Problems with Python installing anything [duplicate]

I've install Python 3.4 and Python 3.6 on my local machine successfully, but am unable to install packages with pip3.
When I execute pip3 install <package>, I get the following SSL related error:
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
Collecting <package>
Could not fetch URL https://pypi.python.org/simple/<package>/: There was a problem confirming the ssl certificate: Can't connect to HTTPS URL because the SSL module is not available. - skipping
Could not find a version that satisfies the requirement <package> (from versions: )
No matching distribution found for <package>
How can I fix my Python3.x install so that I can install packages with pip install <package>?

Step by step guide to install Python 3.6 and pip3 in Ubuntu
Install the necessary packages for Python and ssl: $ sudo apt-get install libreadline-gplv2-dev libncursesw5-dev libssl-dev libsqlite3-dev tk-dev libgdbm-dev libc6-dev libbz2-dev
Download and unzip "Python-3.6.8.tar.xz" from https://www.python.org/ftp/python/ into your home directory.
Open terminal in that directory and run: $ ./configure
Build and install: $ make && sudo make install
Install packages with: $ pip3 install package_name
Disclaimer: The above commands are not tested in Ubuntu 20.04 LTS.

If you are on Windows and use anaconda this worked for me:
I tried a lot of other solutions which did not work (Environment PATH Variable changes ...)
The problem can be caused by DLLs in the Windows\System32 folder (e.g. libcrypto-1_1-x64.dll or libssl-1_1-x64.dll or others) placed there by other software.
The fix was installing openSSL from https://slproweb.com/products/Win32OpenSSL.html which replaces the dlls by more recent versions.

If you are on Red Hat/CentOS:
# To allow for building python ssl libs
yum install openssl-devel
# Download the source of *any* python version
cd /usr/src
wget https://www.python.org/ftp/python/3.6.2/Python-3.6.2.tar.xz
tar xf Python-3.6.2.tar.xz
cd Python-3.6.2
# Configure the build w/ your installed libraries
./configure
# Install into /usr/local/bin/python3.6, don't overwrite global python bin
make altinstall

I had a similar problem on OSX 10.11 due to installing memcached which installed python 3.7 on top of 3.6.
WARNING: pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
Spent hours on unlinking openssl, reinstalling, changing paths.. and nothing helped. Changing openssl version back from to older version did the trick:
brew switch openssl 1.0.2e
I did not see this suggestion anywhere in internet. Hope it serves someone.

In Ubuntu, this can help:
cd Python-3.6.2
./configure --with-ssl
make
sudo make install

Agree with the answer by mastaBlasta. Worked for me. I encountered the same problem as the topic description.
Environment: MacOS Sierra. And I use Homebrew.
My solution:
Reinstall openssl by brew uninstall openssl; brew install openssl
According to the hints given by Homebrew, do the following:
echo 'export PATH="/usr/local/opt/openssl/bin:$PATH"' >> ~/.bash_profile
export LDFLAGS="-L/usr/local/opt/openssl/lib"
export CPPFLAGS="-I/usr/local/opt/openssl/include"

If you are on Windows and use Anaconda you can try running "pip install ..." command in Anaconda Prompt instead of cmd.exe, as user willliu1995 suggests here. This was the fastest solution for me, that does not require installation of additional components.

The problem probably caused by library missing.
Before you install python 3.6, make sure you install all the libraries required for python.
$ sudo apt-get install build-essential checkinstall
$ sudo apt-get install libreadline-gplv2-dev libncursesw5-dev libssl-dev libsqlite3-dev tk-dev libgdbm-dev libc6-dev libbz2-dev
More information in How to Install Python 3.6.0 on Ubuntu & LinuxMint

If you are on OSX and have compiled python from source:
Install openssl using brew brew install openssl
Make sure to follow the instructions brew gives you about setting your CPPFLAGS and LDFLAGS. In my case I am using the openssl#1.1 brew formula and I need these 3 settings for the python build process to correctly link to my SSL library:
export LDFLAGS="-L/usr/local/opt/openssl#1.1/lib"
export CPPFLAGS="-I/usr/local/opt/openssl#1.1/include"
export PKG_CONFIG_PATH="/usr/local/opt/openssl#1.1/lib/pkgconfig"
Assuming the library is installed at that location.

Downgrading openssl worked for me,
brew switch openssl 1.0.2s

I encountered the same problem on windows 10. My very specific issue is due to my installation of Anaconda. I installed Anaconda and under the path Path/to/Anaconda3/, there comes the python.exe. Thus, I didn't install python at all because Anaconda includes python. When using pip to install packages, I found the same error report, pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available..
The solution was the following:
1) you can download python again on the official website;
2) Navigate to the directory where "Python 3.7 (64-bit).lnk"is located
3) import ssl and exit()
4) type in cmd, "Python 3.7 (64-bit).lnk" -m pip install tensorflow for instance.
Here, you're all set.

I tried A LOT of ways to solve this problem and none solved. I'm currently on Windows 10.
The only thing that worked was:
Uninstall Anaconda
Uninstall Python (i was using version 3.7.3)
Install Python again (remember to check the option to automatically add to PATH)
Then I've downloaded all the libs I needed using PIP... and worked!
Don't know why, or if the problem was somehow related to Anaconda.

for osx brew users
my issue appeared related to my python installation and was quickly resolved by re-installing python3 and pip. i think it started misbehaving after an OS update but who knows (at this time I am on Mac OS 10.14.6)
brew reinstall python3 --force
# setup pip
curl https://bootstrap.pypa.io/get-pip.py -o get-pip.py
python3 get-pip.py
# installa pkg successfully
pip install pandas

You can do either of these two:
While installing Anaconda, select the option to add Anaconda to the path.
or
Find these (complete) paths from your installation folder of Anaconda and add them to the environment variable :
\Anaconda
\Anaconda\Library\mingw-w64\bin
\Anaconda\Library\usr\bin
\Anaconda\Library\bin
\Anaconda\Scripts
\anaconda\Library
\anaconda\condabin
Add the above paths to the "Path" system variable and it should show the error no more :)

The ssl module is a TLS/SSL wrapper for accessing Operation Sytem (OS) socket (Lib/ssl.py). So when ssl module is not available, chances are that you either don't have OS OpenSSL libraries installed, or those libraries were not found when you install Python. Let assume it is a later case (aka: you already have OpenSSL installed, but they are not correctly linked when installing Python).
I will also assume you are installing from source. If you are installing from binary (ie: Window .exe file), or package (Mac .dmg, or Ubuntu apt), there is not much you can do with the installing process.
During the step of configuring your python installation, you need to specify where the OS OpenSSL will be used for linking:
# python 3.8 beta
./configure --with-openssl="your_OpenSSL root"
So where will you find your installed OpenSSL directory?
# ubuntu
locate ssl.h | grep '/openssl/ssl.h'
/home/user/.linuxbrew/Cellar/openssl/1.0.2r/include/openssl/ssl.h
/home/user/envs/py37/include/openssl/ssl.h
/home/user/miniconda3/envs/py38b3/include/openssl/ssl.h
/home/user/miniconda3/include/openssl/ssl.h
/home/user/miniconda3/pkgs/openssl-1.0.2s-h7b6447c_0/include/openssl/ssl.h
/home/user/miniconda3/pkgs/openssl-1.1.1b-h7b6447c_1/include/openssl/ssl.h
/home/user/miniconda3/pkgs/openssl-1.1.1c-h7b6447c_1/include/openssl/ssl.h
/usr/include/openssl/ssl.h
Your system may be different than mine, but as you see here I have many different installed openssl libraries. As the time of this writing, python 3.8 expects openssl 1.0.2 or 1.1:
Python requires an OpenSSL 1.0.2 or 1.1 compatible libssl with X509_VERIFY_PARAM_set1_host().
So you would need to verify which of those installed libraries that you can use for linking, for example
/usr/bin/openssl version
OpenSSL 1.0.2g 1 Mar 2016
./configure --with-openssl="/usr"
make && make install
You may need to try a few, or install a new, to find the library that would work for your Python and your OS.

I was having the same issue and was able to resolve with the following steps:
sudo yum install -y libffi-devel
sudo yum install openssl-devel
cd /usr/src
sudo wget https://www.python.org/ftp/python/3.7.1/Python-3.7.1.tar.xz
sudo tar xf Python-3.7.1.tar.xz
cd Python-3.7.1
sudo ./configure --enable-optimizations
# Install into /usr/local/bin/python3.7, don't overwrite global python bin
sudo make altinstall
depending on perms, you may not need sudo.
Results:
Collecting setuptools
Collecting pip
Installing collected packages: setuptools, pip
Successfully installed pip-10.0.1 setuptools-39.0.1
should now be able to run
python3.7 -V
and
pip3.7 -V
When installing packages:
pip3.7 install pandas
or depending on perms, you can also add the --user flag like so:
pip3.7 install pandas --user

In my case with using Mac, I deleted
/Applications/Python 3.7.
because I already had Python3.7 by brew install python3 .
But it was a trigger of the message
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
What I did in my situation
I downloaded macOS 64-bit installer again, and installed.
Double click /Applications/Python3.6/Install Certificates.command and /Applications/Python3.6/Update Shell Profile.command.
Reboot mac
And I am not sure but possibly contributed to succeed is pip.conf. See pip install fails.

I finally solve this issue. These are the detail of my env:
Version of Python to install: 3.6.8
OS: Ubuntu 16.04.6 LTS
Root access: No
Some people suggest to install libssl-dev, but it did not work for me. I follow this link and I fixed it!
In short, I download, extract, build, and install OpenSSL (openssl-1.1.1b.tar.gz). Then, I modify .bashrc file follow this link.
Next, I download and extract Python-3.6.8.tgz. I edit Modules/Setup.dist to modify SSL path (lines around #211). I did ./configure --prefix=$HOME/opt/python-3.6.8, make and make install. Last, I modify my .bashrc. Notice that I do not include --enable-optimizations in ./configure.

I was able to fix this by updating the python version in this file.
pyenv: version `3.6.5' is not installed (set by /Users/taruntarun/.python-version)
Though i had the latest version installed, my command was still using old version 3.6.5
Moving to version 3.7.3

Termux
This worked because i didnt have an existing openssl version installed.
pkg install openssl-tool

If you are on OSX and in case the other solutions didn't work for you (just like me).
You can try uninstalling python3 and upgrade pip3
brew uninstall --ignore-dependencies python3
pip3 install --upgrade pip
This worked for me ;)

(NOT on Windows!)
This made me tear my hair out for a week, so I hope this will help someone
I tried everything short of re-installing Anaconda and/or Jupyter.
Setup
AWS Linux
Manually installed Anaconda 3-5.3.0
Python3 (3.7) was running inside anaconda (ie, ./anaconda3/bin/python)
there was also /usr/bin/python and /usr/bin/python3 (but these were not being used as most of the work was done in Jupyter's terminal)
Fix
In Jupyter's terminal:
cp /usr/lib64/libssl.so.10 ./anaconda3/lib/libssl.so.1.0.0
cp /usr/lib64/libcrypto.so.10 ./anaconda3/lib/libcrypto.so.1.0.0
What triggered this?
So, this was all working until I tried to do a conda install conda-forge
I'm not sure what happened, but conda must have updated openssl on the box (I'm guessing) so after this, everything broke.
Basically, unknown to me, conda had updated openssl, but somehow deleted the old libraries and replaced it with libssl.so.1.1 and libcrypto.so.1.1.
Python3, I guess, was compiled to look for libssl.so.1.0.0
In the end, the key to diagnosis was this:
python -c "import ssl; print (ssl.OPENSSL_VERSION)"
gave the clue library "libssl.so.1.0.0" not found
The huge assumption I made is that the yum version of ssl is the same as the conda version, so just renaming the shared object might work, and it did.
My other solution was to re-compile python, re-install anaconda, etc, but in the end I'm glad I didn't need to.
Hope this helps you guys out.

In the case of using pyenv to manage python installations on Mac OS Catalina, I had to install openssl with brew first and then after that run pyenv install 3.7.8 which seemed to build the python installation using the openssl from homebrew (it even said as such in the installation output). Then pyenv global 3.7.8 and I was away.

On macos, configure python 3.8.1 with the command below will solve the problem, i think it would also work on Linux.
./configure --enable-optimizations --with-openssl=/usr/local/opt/openssl#1.1/
change the dir parameter based on your system.

I've made some PATH changes to mimic part of the Anaconda Powershell Prompt $env:PATH
C:\Users\merheb\Miniconda3;C:\Users\merheb\Miniconda3\Library\mingw-w64\bin;C:\Users\merheb\Miniconda3\Library\usr\bin;C:\Users\merheb\Miniconda3\Library\bin;C:\Users\merheb\Miniconda3\Scripts;C:\Users\merheb\Miniconda3\bin;C:\Users\merheb\Miniconda3\condabin;
And It worked for me.

Building from source was what worked for me on Ubuntu 22.10:
Install OpenSSL manually, tested here with OpenSSL 1.1.1s, extracted then ran:
./config --prefix='/opt/openssl' --openssldir='/opt/ssl'
make
make install
Then with your older Python 3 version (here Python-3.8.16) run:
export LD_RUN_PATH='/opt/openssl/lib'
export CC='gcc-12' # sudo apt install gcc-12
./configure --enable-optimizations \
--with-openssl='/opt/openssl' \
--prefix='/opt/python/3.8' -C
make
make install
Test with:
/opt/python/3.8/bin/python3 -c 'import ssl; print(ssl.OPENSSL_VERSION)'
OpenSSL 1.1.1s 1 Nov 2022

The python documentation is actually very clear, and following the instructions did the job whereas other answers I found here were not fixing this issue.
first, install python 3.x.x from source using, for example with version 3.6.2 https://www.python.org/ftp/python/3.6.2/Python-3.6.2.tar.xz
make sure you have openssl installed by running brew install openssl
unzip it and move to the python directory: tar xvzf Python-3.6.2.tar.xz && cd Python-3.6.2
then if the python version is < 3.7, run
CPPFLAGS="-I$(brew --prefix openssl)/include" \
LDFLAGS="-L$(brew --prefix openssl)/lib" \
./configure --with-pydebug
5. finallly, run make -s -j2 (-s is the silent flag, -j2 tells your machine to use 2 jobs)

I had the same issue trying to install python3.7 on an ubuntu14.04 machine.
The issue was that I had some custom folders in my PKG_CONFIG_PATH and in my LD_LIBRARY_PATH, which prevented the python build process to find the system openssl libraries.
so try to clear them and see what happens:
export PKG_CONFIG_PATH=""
export LD_LIBRARY_PATH=""

Ok the latest answer to this, as of now don't use Python 3.8, use only 3.7 or less , because of most of the libraries fail to install with the above error

Installing with pip using custom compiled Python can't use SSL

I'm trying to install Flask using pip. I've been following this tutorial, which instructs me to compile Python 3. pip install Flask gives an error that the SSL module is not available, then fails to install Flask.
While compiling, I had to sudo apt-get install zlib1g-dev to compile zlib. Do I have to install something to compile the SSL module too?
$ pip install flask
pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.
Collecting flask
Could not fetch URL https://pypi.python.org/simple/flask/: There was a problem confirming the ssl certificate: Can't connect to HTTPS URL because the SSL module is not availabe. - skipping
Could not find a version that satisfies the requirement flask (from versions: )
No matching distribution found for flask
$

Most modern Linux distributions, including Mint, already have Python 3 installed, just run python3. If it is not installed, install it with sudo apt-get install python3 (or the equivalent for your distribution). You should not be compiling it yourself.
Create a virtualenv, then install Flask there.
mkdir myproject && cd myproject
python3 -m venv env
. env/bin/activate
pip install flask
If, for some reason, you still want to compile it yourself, then just as you had to install the development headers for zlib, you have to do the same for openssl (and a few others if you want a standard build). sudo apt-get install libssl-dev

SSL backend error when using OpenSSL

I was trying to install pycurl in a virtualenv using pip and I got this error
ImportError: pycurl: libcurl link-time ssl backend (openssl) is different from compile-time ssl backend (none/other)
I read some documentation saying that "To fix this, you need to tell setup.py what SSL backend is used" (source) although I am not sure how to do this since I installed pycurl using pip.
How can I specify the SSL backend when installing pycurl with pip?
Thanks

for most people
After reading their INSTALLATION file, I was able to solve my problem by setting an environment variable and did a reinstall
# remove existing `pycurl` installation
pip uninstall pycurl
# export variable with your link-time ssl backend (which is openssl above)
export PYCURL_SSL_LIBRARY=openssl
# then, re-install `pycurl` with **no cache**
pip install pycurl --no-cache-dir
There could be other solution out there but this works perfectly for me on a virtualenv and pip installation.
Some people have a different error message complaining about nss instead of openssl
ImportError: pycurl: libcurl link-time ssl backend (nss)
(the key part is nss) so you have to do something different for this error message:
pip uninstall pycurl
pip install --no-cache-dir --compile --compile-options="--with-nss" pycurl

helloworld2013's answer is correct, but the key is matching the SSL library that pycurl is expecting. The error will be something like:
pycurl: libcurl link-time ssl backend (<library>) is different from compile-time ssl backend (<library> or "none/other")
To fix it, you have to use the library pycurl is expecting. In my case, my error was "pycurl: libcurl link-time ssl backend (nss) is different from compile-time ssl backend (openssl)", so my fix was:
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=nss
pip install pycurl

With macOS 10.13, a brew-installed openSSL, and virtualenv, I was successful with:
# cd to your virtualenv, then…
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=openssl
export LDFLAGS=-L/usr/local/opt/openssl/lib
export CPPFLAGS=-I/usr/local/opt/openssl/include
pip install pycurl --compile --no-cache-dir

With pip 7.1 you can put the following in your requirements file:
pycurl==7.19.5.1 --global-option="--with-nss"
Simply replace nss with the relevant ssl backend library.

The method to fix the pycurl after Mac OS High Sierra update:
Reinstall the curl libraries to use OpenSSL instead of SecureTransport
brew install curl --with-openssl
Install pycurl with correct build-time environment and paths
export PYCURL_SSL_LIBRARY=openssl
pip uninstall pycurl
pip install --no-cache-dir --global-option=build_ext --global-option="-L/usr/local/opt/openssl/lib" --global-option="-I/usr/local/opt/openssl/include" --user pycurl

This worked for me:
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=nss
easy_install pycurl
None of this worked for me (note the difference is simply easy_install vs pip):
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=[nss|openssl|ssl|gnutls]
pip install pycurl
#xor
curl -O https://pypi.python.org/packages/source/p/pycurl/pycurl-7.19.3.1.tar.gz
#...
python setup.py --with-[nss|openssl|ssl|gnutls] install

I had this problem for days. Finally with the help of other answers here (mainly Alexander Tyapkov's) I got it working for AWS Elastic Beanstalk.
Manual install (connecting with SSH):
sudo pip uninstall pycurl
curl -O https://pypi.python.org/packages/source/p/pycurl/pycurl-7.43.0.tar.gz
sudo pip install pycurl-7.43.0.tar.gz --global-option="--with-nss"
IMPORTANT: Please note that you have to make sure you are using the currect version of Python and PIP, otherwise you might be compiling it for Python 2.x and using v3.x.
Auto-install in Elastic Beanstalk:
files:
"/usr/local/share/pycurl-7.43.0.tar.gz" :
mode: "000644"
owner: root
group: root
source: https://pypi.python.org/packages/source/p/pycurl/pycurl-7.43.0.tar.gz
commands:
01_download_pip3:
# run this before PIP installs requirements as it needs to be compiled with OpenSSL
command: 'curl -O https://bootstrap.pypa.io/get-pip.py'
02_install_pip3:
# run this before PIP installs requirements as it needs to be compiled with OpenSSL
command: 'python3 get-pip.py'
03_pycurl_uninstall:
# run this before PIP installs requirements as it needs to be compiled with OpenSSL
command: '/usr/bin/yes | sudo pip uninstall pycurl'
04_pycurl_download:
# run this before PIP installs requirements as it needs to be compiled with OpenSSL
command: 'curl -O https://pypi.python.org/packages/source/p/pycurl/pycurl-7.43.0.tar.gz'
05_pycurl_reinstall:
# run this before PIP installs requirements as it needs to be compiled with OpenSSL
command: 'sudo pip install pycurl-7.43.0.tar.gz --global-option="--with-nss"'
container_commands:
09_pycurl_reinstall:
# run this before PIP installs requirements as it needs to be compiled with OpenSSL
# the upgrade option is because it will run after PIP installs the requirements.txt file.
# and it needs to be done with the virtual-env activated
command: 'source /opt/python/run/venv/bin/activate && pip3 install /usr/local/share/pycurl-7.43.0.tar.gz --global-option="--with-nss" --upgrade'
I had this problem because I was trying to configure Celery 4 with Django 1.10 in Elastic Beanstalk. If that's your case, I wrote a full blog post about it.

I'm on CentOS 7. I tried all of the above and couldn't get anything to work. It turns out I needed to run these as a root user. So if you're having trouble, try any of the above solutions as a root user. As an example, here is what worked for me:
su -
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=[nss|openssl|ssl|gnutls]
pip install pycurl
Of course, all the usual disclaimers about running as a root user apply.
Note: [nss|openssl|ssl|gnutls] in the code above means to pick one, and don't include the square brackets or pipes. The person who asked the original question would have chosen openssl. In my particular case, I chose nss. Your error message should tell you which choice to make.
2019 Edit: Doing a sudo pip install might cause a problem with the machine's system install of Python. Perhaps try working in a Python virtual environment and install the packages there. If that doesn't work, the sudo trick in my answer is probably one of the last options to consider.

You can download the tar.gz file from here. Then extract it into a folder. You'll find a setup.py file there. Run the command over there that the site mentioned. For example:
python setup.py --with-[ssl|gnutls|nss] install
FYI: I tried to install pycurl at my windows, but I couldn't. But did it on my linux.

I am running this on OS X and some of the above solutions weren't working. Similar to Edward Newell's comment the PYCURL_SSL_LIBRARY variable seemed to have been completely ignored.
Further reading of the PycURL installation doc revealed the following:
pip may reinstall the package it has previously compiled instead of recompiling pycurl with newly specified options
Therefore, I had to force it to compile with:
pip install --compile pycurl
That works on a number of cases. However, I did run into a few systems that continued to ignore the variable so, similar to maharg101's answer, I resorted to the install options which through pip can be set like this:
pip install pycurl --global-option="--with-[ssl|gnutls|nss]"
where you select one of the three options inside the square brackets. Notice that the available option is ssl and not openssl. If you specify --with-openssl you'll get an error. Also note that if you were messing around with the PYCURL_SSL_LIBRARY variable and switching it to funky values to see what would happen this last command will definitely catch it and throw an error if the value is set but not valid.

For anyone having problem inside PyCharm CE on macOS
Mojave this is how i got it working in venv:
specify version: 7.43.0.1
Options: --install-option=--with-openssl --install-option=--openssl-dir=/usr/local/opt/openssl

Reinstallation of curl
I tried every suggestion from this discussion but no one worked for me. As solution I have reinstalled curl and curlib. After that I was able to install pycurl with ssl support inside environment.
At start:
'PycURL/7.43.0 libcurl/7.47.0 GnuTLS/3.4.10 zlib/1.2.8 libidn/1.32
librtmp/2.3'
Part 1.Re/Installation with pip
Firstly I have removed pycurl from virtualenv using pip as was suggested previous answers:
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=openssl
pip install pycurl --global-option="--with-openssl"
The idea here is that package was cached and we just reintstall it with openssl option.
I also tried to recompile pycurl with pip using:
pip install pycurl --compile pycurl --no-cache
..but had the same error after running:
python
import pycurl
pycurl.version
ImportError: pycurl: libcurl link-time ssl backend (gnutls) is
different from compile-time ssl backend (openssl)
Part 2. Installation from tar
After previous method didn't work I have decidede to install pycurl from tar with:
curl -O https://pypi.python.org/packages/source/p/pycurl/pycurl-7.43.0.tar.gz
sudo tar -xzvf pycurl-7.43.0.tar.gz
cd pycurl-7.43.0/
sudo python setup.py --with-ssl install
It has installed pycurl globally but not within virtualenv. I also didn't check if it was installed with SSL support or not but think that still without ssl.
Part 3. Reinstallation of curl and curllib
Finally I understood that pycurl doesn't installs normally into environment because global curl and libcurl are compiled with gnutls.
Before starting check it with:
curl-config --configure
One of the output lines will be
'--without-ssl' '--with-gnutls'
To recompile it:
Firstly remove curl:
sudo apt-get purge curl
Install any build dependencies needed for curl
sudo apt-get build-dep curl
Get latest (as of Dec 20, 2016) libcurl
mkdir ~/curl
wget http://curl.haxx.se/download/curl-7.51.0.tar.bz2
tar -xvjf curl-7.51.0.tar.bz2
cd curl-7.51.0
The usual steps for building an app from source
./configure
./make
sudo make install
If openssl installed correctly then configure will find it automatically. The output will be:
curl version: 7.51.0
Host setup: x86_64-pc-linux-gnu
Install prefix: /usr/local
Compiler: gcc
SSL support: enabled (OpenSSL) ...
Resolve any issues of C-level lib location caches ("shared library cache")
sudo ldconfig
Now try to reinstall pycurl within environment:
curl -O https://pypi.python.org/packages/source/p/pycurl/pycurl-7.43.0.tar.gz
pip install pycurl-7.43.0.tar.gz --global-option="--with-openssl"
The result should be:
python
import pycurl
pycurl.version
'PycURL/7.43.0 libcurl/7.51.0 OpenSSL/1.0.2g zlib/1.2.8 librtmp/2.3'

I tried everything here on macOS 10.13 with no success. Then I found https://gist.github.com/webinista/b4b6a4cf8f158431b2c5134630c2cbfe which worked:
brew install curl --with-openssl
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=openssl
export LDFLAGS=-L/usr/local/opt/openssl/lib;export CPPFLAGS=-I/usr/local/opt/openssl/include; pip install pycurl --compile --no-cache-dir
This worked for me both when not using a virtualenv and within a virtualenv.

This worked for me:
pip install --compile --install-option="--with-openssl" pycurl

Not sure if this is because of running in a virtualenv, but on CentOS 7 these solutions weren't working for me; the compiled objects were still being grabbed from the cache dir when I was reinstalling. If you're running into the same problem after trying other solutions here, try the following:
pip uninstall pycurl
export PYCURL_SSL_LIBRARY=[nss|openssl|ssl|gnutls]
pip install pycurl --no-cache-dir

Error:
ImportError: pycurl: libcurl link-time ssl backend (openssl) is different from compile-time ssl backend (none/other)
This worked for me, Mac 10.13, python 3.5, pycurl import worked after installing like this
pip3 uninstall pycurl;
pip3 install --compile --install-option="--with-openssl" pycurl

After being stuck on this for a long time, I found out that apple stopped including OpenSSL headers since OS X 10.11 El Capitan.
how to fix?
1) brew install openssl
2) echo 'export PATH="/usr/local/opt/openssl/bin:$PATH"' >> ~/.bash_profile (or .zshrc for zsh, etc)
3) pip uninstall pycurl
4) pip install --install-option="--with-openssl" --install-option="--openssl-dir=/usr/local/opt/openssl" pycurl

Same problem on amazonlinux - solved
I had this problem while creating a docker image based on amazonlinux, installing python3.7 and adding the pycurl module.
All other python modules were installed correctly except pycurl.
After trying many of the solutions proposed in the threads linked to this problem I finally solved my problem by using following commands for installation of all the pieces.
yum -y install python3 python3-devel gcc libcurl-devel aws-cli openssl-static.x86_64
then installed other modules like psycopg2-binary, requests, certifi using:
pip3 install --user --no-cache-dir -r requirements.txt
and finally installed pycurl module using:
pip3 install --user --global-option="--with-openssl" --no-cache-dir pycurl
and passing here the openssl global option.
The installation of the static library openssl-static.x86_64 solved the problem in my case as using global option used by the second pip3 command.

For python 2.7
sudo apt-get install build-essential libssl-dev libffi-dev python-dev
For python 3.5 also install the next:
sudo apt-get install python3.5-dev
Download the latest pycurl-7.43.0.tar.gz (md5) Source from pypi https://pypi.python.org/pypi/pycurl/7.43.0#downloads
and run the next command:
python setup.py --with-openssl install
Also you can do it into python environment:
(test_env)user#pc:~/Downloads/pycurl-7.43.0$ python setup.py --with-openssl install

pip install -U pip
if [ "$(curl --version | grep NSS 2>/dev/null)" ]; then
pip install --compile --install-option="--with-nss" pycurl
else
pip install --compile --install-option="--with-openssl" pycurl
fi

I encountered this problem and Sanket Jagtap's answer worked for me. I tried the answer with the most votes answer but it did not work.
My openssl old version is 1.0.1t, I think reinstalling openssl may solve this problem.
--- pycurl's openssl backend time....
I rebuilt the latest openssl and tried this answer. Check this out.
pip install --compile --install-option="--with-openssl" pycurl
This worked for me.
i recommend we should reinstall our openssl for try..

Following worked for me with Python3.6
MacOS High-Sierra
sudo pip3 uninstall pycurl
sudo pip3 install --compile --install-option="--with-openssl" pycurl
CentOS 7
sudo pip3 uninstall pycurl
sudo pip3 install --compile --install-option="--with-nss" pycurl

This link sums up the reason why the errors occur and gives a clear instruction to fix the problem.
https://cscheng.info/2018/01/26/installing-pycurl-on-macos-high-sierra.html
For me, the problem occurred when I upgraded to High-Sierra from El
Captain.

FWIW, I ran into a lot of issues getting this working via AWS Elastic Beanstalk and finally was able to get it working with:
packages:
yum:
openssl-devel: []
libcurl-devel: []
container_commands:
# Reinstall PyCurl with correct ssl backend
05_reinstall_pycurl:
command: |
pip install --upgrade pip
pip uninstall -y pycurl
pip install --global-option='--with-openssl' pycurl

Recently while upgrading a Django project I had the similar error. But this time setting the environment variable did not work. So I had to set both environment variable export PYCURL_SSL_LIBRARY=openssl and pass the flag --global-option="with-openssl".
The original answer was posted on this page

export CPPFLAGS=-I/usr/local/opt/openssl/include
export LDFLAGS=-L/usr/local/opt/openssl/lib
pip install pycurl --global-option="--with-openssl"

Develop Reference

Python is a programming language that lets you work quickly and integrate systems more effectively.