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Python GUI without 'video system'

I'm currently at a crossroads. I'm somewhat versed in Python (2.7) and would really like to start getting into GUI to give my (although mini) projects some more depth and versibility.
For the most part, my scripts don't use anything graphical so this is the first time I'm dipping my toes in this water.
That said, I've tried using pygame and tkinter but seem to fail at every turn to get something up and running (although I had some slight success with pygame)
Am I correct to understand that for both I need X started in order to generate any type of interface, and with that, so I need X to get any type of input (touchscreen presses)?
Thanks in advance!

In order to use tkinter, you must have a graphics system running. For Windows and OSX that simply means you need to be logged in (ie: can't run as a service). For linux and other unix-like systems that means that you must have X running.
Neither tkinter nor any of the other common GUI toolkits will write directly to the screen.

I'm gonna give an alternative answer. If you know HTML, CSS and Javascript (or have time to give it a try) I would recommend using Flask, http://flask.pocoo.org/.
With flask you can create websites but you can also (as I am using it) let it be your GUI. It will work on any device and looks really good :).

Using Python, could I automate the process of getting excel data into a CRM system?

I've done a little basic coding in Java, VBA and C++ before but still a complete newbie, I'm trying to understand what exactly it is that I could do with Python and how it would be useful.
For example, at my appointment-setting job I get customer data in an Excel sheet from my boss, that I'm supposed to put into the CRM system before calling them. It takes me probably at least 5 minutes each time and it's very tedious. Could I automate this process using Python? I've been looking into learning Python recently and thought this might be a good first goal-project in that case, if it's possible and not too difficult to do.
Thanks in advance.

I'm not sure what CRM is, but pulling excel content into your python program is easy. I have used this (https://automatetheboringstuff.com/chapter12/) for processing excel content in the past.

Yes, you can use Python for this. Automate the Boring Stuff with Python is a good resource for getting started. Once you understand how to do this, you need to find out if your CRM has some sort of API or tool that will allow you to post data with your Python code. Chances are good that it does.

Drawing meteorological maps in python

I found a user friendly way plotiing meteorological maps with python. I found this flight path tool, http://www.aviationweather.gov/flightpath2?gis=off , and i want to make something like this in python. I have made the scripts retrieving the data and plotting the maps but i want to make the interface. Is it difficult? Do you have any ideas?

Are you wanting to make a web-based interface? If so, I suggest maybe Django. If you want just a script with some nice GUI on a local machine, I think Qt is easy to use. I can't run the java file from aviationweather.gov (or rather, do not wish to) so I don't know what the interface is like. But using either Django or Qt, I think those are the tools I would start with.

Check out the video here.
https://blogs.msdn.microsoft.com/visualstudio/2016/03/22/introducing-r-tools-for-visual-studio-3/
Start watching about 7 minutes into the video. I think that will be a great learning experience for you, and should get you going in the right direction.

Best option for making a collection of python code portable?

Here are the facts:
I have a collection of python scripts that work together as part of a program
It takes a user input and outputs .docx and .excel files
Right now, only executable through command-line/editor (i.e. you call one script, it does the rest)
Non-CS people have difficulties downloading the necessary modules, and running the program
I want to make my program easily executable/portable to different OSs. So far, I have the following options:
Create a website that takes input visually, and does what it has to do. How do I get the website to refer to my code? Do I have to put it in some sort of web server?
Create an executable that others can simply run (Not sure if this is possible)
Create a GUI that does everything visually.
What are the pros and cons of each one of these options? Which one would you say is most feasible?
My apologies if I said something silly. I'm still learning most of this stuff.
Thank you!

Strategy to Implement Linked Processes in Python

Hey everyone I have a large scope type question that I'd really appriciate feedback/insight on.
I'm a newish programer and am Developing an 'Engine Development Enviorment' for fun at work. I have a program that makes alot of run files, and I have another program that manages batched/local multiprocessed simulations.
I want them to work seamlessly together, but I only want one instance of the 'BatchMaster' to run locally (from the taskbar). I also do alot of scripting type stuff for exploratory data analysis and would love the ability to launch simulations in a single line of code like the following.
import enginemodels
aetd = enginemodels.aetd(bleed='ON')
results = aetd.run(altitude=80000,mach=5,tempsls=60)
I'm would like to have my engine model run method send input to the 'BatchMaster' process.
My question is two parts:
1) How to do you find a multiprocessing instance in windows and send it information?
2) If there isn't an instance of that program, how do you launch it?
Thanks for any feedback or insight you can provide!
This will really help out alot of people at my workplace who aren't good at programming, and do most of their work making files via copy paste.